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Arishta laxanas are certain ominous signs and symptoms observed in and around the patient that indicate patient's imminent death. Knowledge of Arishta laxanas is considered to be the important tool for a vaidya to predict lifespan and approximate duration of remaining life of a patient. Knowledge of Arishta laxanas is thus believed to be the part of clinical prognosis exclusively described in Ayurveda and is certainly the example of superior intelligence, keen observation and deep study of Sharira (normal anatomy and physiology) of patient by our ancient Ayurveda scholars. It is a unique contribution of Ayurveda towards clinical diagnosis which is disappearing faster from the technology led medical science of today's world.

Introduction
Ayurveda is a systematic knowledge of medicine which defines Ayu(life) as a combination of sharira, indriyas, satva and atman with an objective of maintaining dhatus in their
equilibrium state. Each section of classical Ayurveda treatises focuses on the betterment of this Ayu. The beginning of Ayu and the end of this Ayu is therefore should be known precisely. It is belived that, Ayu starts with union of male and female beejas (gamets) and Atman in the womb of the mother. In this way the physical body development and growth starts. After a cetain period the growth stops and degeneration of the mortal components of life named 'Sharira' starts. Life ends when the union of Sharira, Atman, Indriya and Manas dissociates. Thus, one has to keenly observe the various stages of Ayu and use Ayurveda knowledge accordingly to achieve maximum benefits. In this context few sections in Classical Ayurveda Samhitas were designed to tell the Ayu(life span) of the diseased person with the help of arishta. Arishtas are believed to be the fatal signs of death which definitely occur in diseased person before death just like flowers indicates upcoming fruit and smoke indicates agni (fire) and cloud indicate rain. Various Ayurveda acharyas have described these ominous signs which indicate bad prognosis and imminent end of one's Ayu so as to help Vaidya to plan or stop treatment. Few thousand years ago, when advanced technology was not used in the practice of medicine and dignosis was used to be merely clinical, this knowledge of Arishta laxanas enabled practitioners to foresee the imminent death and act accordingly.

Definition of Arishtas

Acharya Vagbhata has defined Arishtas as the signs and symptoms which are definite indicator of death. He has mentioned the synonym Rishta for Arishta laxanas.

Ashtanga Hrdayam Sharirasthanam Adhyaya 5 Sutra 4-5- https://archive.org/details/Ashtanga.Hridaya.of.Vagbhata/page/n603

रूपेन्द्रियस्वरच्छायाप्रतिच्छायाक्रियादिषु
अन्येष्वपि च भावेषु प्राकृतेष्व्निमित्ततः
विकृतिर्वा समासेन रिष्टं तदिति लक्षयेत् (Asht. Hrda. 5.4-5)



Place in Ayurveda samhitas

Ayurveda treatises have stressed that, before going to start treatment of any disease physician should assess for Arishṭa lakshanas. Thus, even before expounding the treatment for various rogas, most of the Samhitas have dedicated either an entire Sthanam (section) or a part of it for offering the knowledge of Arishta laxanas. Different acharyas of ayurveda described them in different sthana of their text. Acharya Charaka contributed a separate sthana for assessment of Arishṭa lakshanas as Indriyasthanam.
Acharya Sushruta in sutrasthanam of Sushruta Samhita & Acharya vagbhata in sharirsthanam of Ashtanga Hrdayam. All of them have emphasized that a physician must keep a keen observation on such fatal signs to achieve success in treatment, fame and prosperity.

Indriya sthana of Charaka Samhita

Indriya Sthana is a unique section of Charaka Samhita;the Brihatrayi famous for its Chikitsa aspects. The inclusion of the Indriya Sthana before Chikitsa Sthana have added much more clarity and importance to the latter .

The word Indra means Prana. Chakrapani says it is Aatmavaachi i.e refers to 'Atman' in this context. In perspective of Indriya Sthana ‘Indriya’ means the signs and symptoms of life approaching its end. Such signs and symptoms that can be directly observed by visual and other faculties are described in this Sthana.

Acharya Charaka, in the Sutra Sthana states that a physician loses his fame, learning and wealth by attempting to cure patients with incurable illnesses.The importance of Indriya Sthana is for the selection of a curable patient. Each of the chapter differs in its intention and approach. A detailed introspection is needed to understand the reasons for these different approaches. Very few attempts have been done to evaluate the approach used in Indriya Sthana. The applications regarding this important Sthana need to be reviewed in the light of contemporary aids of medical science. The details of examinations mentioned and their possibilities are also another area concerned. Since Indriya Sthana is not brought to focus, it becomes important to understand the literary as well as observational applications of this Sthana.


Importance of Arishta knowledge

Ayulakhshan were also stated and if physician see those (ayulakshana) signs and symptoms then without wasting any time a physician should start his treatment. Hence a physician must have a keen observation in identifying the arishtalakshana as well as ayulakshana.

Acharya Vagbhata in Ashtanga Hrdayam says that,

अरिष्टं नास्ति मरणम् दृष्टरिष्टं च जीवितम् (Asht. Hrda. 5.२)

Similarly Achrya Charaka mentions that,

अप्येवं तु भवेत् पुष्पं फलेनाननुबन्धि यत्| फलं चापि भवेत् किञ्चिद्यस्य पुष्पं न पूर्वजम्

न त्वरिष्टस्य जातस्य नाशोऽस्ति मरणादृते| मरणं चापि तन्नास्ति यन्नारिष्टपुरःसरम्

Charak sutra from Charaka Indriya 2/4-5

Meaning: The flower may sometimes be devoid of fruits and sometimes even the fruits may be produced without being preceded by flowers. But once an arishta manifests, it doesn’t depart without ensuing in death. Conversely, death can not occur without earlier manifestation of arishta.


Failure to understand Arishtas

Illusion abobut Arishtas

Acharya Vagbhata has clearly mentioned that one may fail to recognize the Arishtas or differentiate them from clinical features of diseases. Arishta like clinical features might be seen even when the Doshas are present in even more than their excess levels.

दोषाणामपि बाहुल्याद्रिष्टाभासः समुद्भवेत् (Asht. Hrda. 5.३)

This inability to identify and differentiate between Arishtas and clinical features of excessive levels of Doshas might cause physician to land in difficult situation. This happens because of Prajnaparadha of the physician making the Vaidya and Rugna suffer. Arishtas are wrongly interpreted due to subtle nature of these symptoms, ignorance or stupidity of the physician or because such symptoms are very closely followed by the death of the patient.[4].

मिथ्यादृष्टमरिष्टाभमनरिष्टमजानता| अरिष्टं वाऽप्यसम्बुद्धमेतत् प्रज्ञापराधजम्||६||

Meaning: An ignorant person may sometimes wrongly perceive symptoms presenting in an individual as arishta lakshana and sometimes he may even not recognize the arishta lakshana presenting in an individual, all this is the result of intellectual errors

Ways to overcome Arishta laxnas
Acharya Sushruta has briefly mentioned the exceptions for every death followed by appearance of Arishta laxanas. He says that even though the death is certain once Arishtas appear, there are certain exceptions or ways which have capacity to ward off this impending death.
ब्राह्मणैस्तत् किलामलैः |
रसायनतपोजप्यतत्परैर्वा निवार्यते ||५||
Sushruta Samhita Sutrasthanam Adhyaya 28 Sutram 5

रिष्टेऽपि मरणनिवृत्तिमुपायविशेषैराह- ब्राह्मणैरित्यादि| किलशब्दोऽत्रागमार्थं सूचयति; एवं किल आगमे प्रतिपादितमित्यर्थः| अमलैरिति रागादिदोषरहितैः| ब्राह्मणेभ्योऽपरानपि दर्शयन्नाह- रसायनतपोजप्येत्यादि|- रसायनपरा इति स्वभावव्याधिनिवारणविशिष्टौषधचिन्तकाः, ते रसवीर्यौषधप्रभावेण मरणं निवारयन्ति| तथा तपःपराः तपस्विनः, तेऽपि विशिष्टतपःप्रभावेण मरणं निवारयन्ति | जप्यपराः सिद्धमन्त्रचिन्तकाः, तेऽपि मन्त्रशक्तियुक्ताः पञ्चत्वं निषेधयन्ति | एतच्च नियतानियतरिष्टविषयं ज्ञेयम्||५||

This means Arishta are always resulted by death unless warded off by following factors:
• Blessings of the holy pure hearted Brahman.
• With the help of divyara sayanaaushdhi (drug).
• With the grace of siddha yogi [5]



Types of Arishtas
Arishtas are classified in 2 types on the basis of certainty of death (Ashtanga Hrdayam Sharirasthanam Adhyaya 5 Sutra 2) (Nipane Mayur S et al / Int. J. Res. Ayurveda Pharm. 9 (1), 2018)
Sthayi arishta
Sthayi arishta means arishta lakshan which are definite signs of death. For.eg smoke before fire these symptoms associated with physical constituent
Asthayi arishta
Asthayi arishta means arishta lakshan which are not always resulted in diseased; for e.g. Cloud before rain,Charaka acharya stated sometimes vitiated doshas shows symptoms similar to arishta lakshan but they will disappear with dosha saamya avashtha.


Various Arishtas

Mahesh Hirulal: Review on Indriya sthāna of Charaka Samhitha AAMJ 2016; 3:779 – 783

Varna Arishta

Swara Arishta

Gandha Arishta

Rasa Arishta

Sprasha Arishta

Indriya Arishta

Arishtas related to Purvarupas : Ominous prodromal symptoms of diseases

Duration specific Arishtas

Disease specific Arishtas



Significance of Arishta laxanas in today's era
Even though all of the determinants (i.e., signs and symptoms) cannot be explained by rational scientific parameters (as evident by the references above to paranormal and occult sciences), some of these signs and symptoms have been documented and reported as having been experienced by people in various parts of the world. Within the treatise Charak Samhita, physicians are instructed to thoroughly examine the patient for certain signs that indicate terminal illness and investigate using biomarkers. The treatise then advises physicians to stop any therapeutic treatment being given to such terminal patients and provide them palliative care instead. In the present era, with advancements in medical sciences, many arishta lakshanas are well treatable and cannot be considered as "predictors" of death as they used to even a few centuries back. However, these signs and symptoms could serve as important indicators of prognosis of disease and therefore, would be helpful in prompt management to save life of patients.
http://www.carakasamhitaonline.com/mediawiki-1.28.2/index.php?title=Indriya_Sthana

In today’s clinical practices estimating prognosis typically receives less attention than diagnosing and treating disease. Yet, many clinical decisions are not fully informed unless the patient’s prognosis is considered. Critical prognostic information, physicians will be better equipped to make clinical decisions that are aligned with their patients’ values, preferences and goals of care.[7]


Nipane Mayur S et al / Int. J. Res. Ayurveda Pharm. 9 (1), 2018
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