Rasashastra (रसशास्त्रम्)

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Rasashastra (Samskrit रसशास्त्रम्) deals with Indian alchemy. The term literally means the “Science of Mercury”. Apart from its primary domain of alchemy, it is also one of the most popular sections of Ayurveda medicine which offers knowledge regarding use of mineral and animal sourced medicinal substances. Rasashstra provides knowledge about methods required to purify and modify these substances to make them bio-compatible, safe and efficient as medicines. Various herbs, substances like milk, urine, oils are used in specifically designed processing techniques in order to carry out these changes in raw drugs. The medicinal substances obtained in this way have extensive therapeutic utility, instantaneous efficacy with smaller dosage.

Introduction

Medicines used in Ayurveda are sourced from plants, metals, minerals or animals. As per the principles of Ayurveda, there is not a single substance in the Universe which does not have a potential to be used as a drug, provided it is used judiciously by the learned vaidya at right place. The most valued classical treatises of Ayurveda the Brihatrayee and Laghutrayee mainly focus on use of plant derived medicines. However, some instances of use of medicinal substances derived from metals and animals are found at places. Development of Rasashstra took place in later times and use of metal, mineral and animal derived substances then became popular part in Ayurveda's pharmacotherapeutics.

Medicines used in Ayurveda

Ayurveda acharyas have described 3 types of medicinal substances on the basis of their source. [1]

  1. Audbhid : Plant derived substances e.g. leaves, barks, roots, stems, fruits, seeds, shoots etc. of herbs
  2. Jangama : Animal derived substances e.g. milk, meat, blood, urine
  3. Parthiva : Metals and minerals derived substances e.g. Mercury, Sulfur, Iron, gold, silver, Arsenic etc.

Although the raw material from preparation of various medicinal formulations is obtained from these varied resources, it is used in medicines only after these undergo rigorous processing methods known as 'Samskaras' to remove their undesired and hazardous effects and enhance the organic nature to make them bio-compatible. [2]

History of Rasashstra

Emergence of Ayurveda, its descent to earth and transfer of this knowledge through oral tradition are known to be the events from 'Vaidika era'. This was the time when all other classical treatises and mainly Vedas were developing. During this time, emphasis was given on strengthening and maintenance of the health by eliminating the harmful components from lifestyle to regain the original state of health and well-being. The objective of this system was to facilitate smooth passage of an individual towards ‘Moksha’. This was followed by the era of ‘Samhitas’, recognized by the works of great scholars of ‘Ayurveda’ like ‘Maharshi Punarvasu Atreya’ and his disciples ‘Agnivesha’, ‘Bhela’, 'Jatukarna', 'Parashara', 'Harita' etc. These ancient scholars although stressed the importance of maintenance of health like their predecessors, also expanded their vision to pharmacotherapeutics. The therapeutic use of herbs, animal products and metals was extensively described in their works. However, more emphasis was given on the use of herbs and their variety of formulations while describing treatment for illness. Use of herbs as medicine was more popular since herbs being more familiar and assimilable in the human body. Animal products like milk and urine were primarily used while making formulaitons and also as an adjuvants for the medicine. Minerals and metals were also used but their use was not as extensive as herbs. Metals and minerals were considered difficult for absorption and assimilation and thus, they were purified, processed and their formulations were prepared along-with the the herbs. Intensive processing of metals and minerals ensured safety, bio-compatibility and efficacy.[1]

It was from the time of the great Buddhist Sage Naagaarjuna that, Rasashastra evolved as the specialized branch of Rasashstra under the umbrella of Ayurveda medicine. Naagaarjuna is considered as ‘Father of Rasashaastra’. It is believed to have come into its proper existence with its scientific classification and documentation around 8th century.

Naagaarjuna proclaimed

Siddhe Rase Karishyaami Nirdaridryamidam jagat” -

meaning that I am experimenting with the mercury to eliminate poverty from this world.

The main foundation being the concept that the objective of the science of mercury is not limited to Alchemy (Dhaatuvaada) but also to maintain health and strengthen the body for achieving Mukti i.e. ultimate salvation- the concept is incorporated in the sloka as :

“Na Ca Rasashaastram Dhaatuvaadaartham Iti Mantavyam, Dehavedhadvaaraa Muktirev Paramaprayojanaat.” (Anonymous-2004).

Naagaarjuna is also known for his extraordinary acumen in processing mercury with respect to its alchemic and therapeutic use. With the advent of Mercury, a miracle substance in those days, a new class of drugs termed as ‘Rasaushadhi’ with a new science termed as ‘Rasashaastra’ appeared on the horizon of ‘Ayurvedic system of medicine’.

‘Rasashaastra’ can be defined as a science of study of mineral and metallic substances with respect to their therapeutic utility including processing of these substances to prepare a drug. In today’s scientific parlance ‘Rasashaastra’ can be equated with ‘Iatrochemistry’. Although ‘Rasashastra’ deals with therapeutic processing and use of all minerals and metals, the study is dominated by knowledge about mercury and techniques of its processing. The science is named after mercury - ‘Rasa’ being a synonym of ‘Mercury’. Physicians using ‘Rasaushadhi’ in the management of disease are known as ‘Rasa-vaidya’. Rasa-vaidyas were supposed to be superior to their professional counterparts using surgical procedures and plants drugs for treating diseases.[1]

Medicinal substances used in Rasashastra

(TBE)Although ‘Rasashastra’ deals with therapeutic processing and use of all minerals and metals, the study is dominated by knowledge about mercury and techniques of its processing. The science is named after mercury - ‘Rasa’ being a synonym of ‘Mercury’. Physicians using ‘Rasaushadhi’ in the management of disease are known as ‘Rasa-vaidya’. The mineral and metallic substances used in Ayurvedic drugs are classified in different ways.

Generally these drugs are classified in to four distinct classes named-

Rasa : The class of ‘Rasa’ is predominantly possessing ‘Rasaayana’ (adaptogenic effect) effect.

Dhaatu : Dhatus are grouped together on account of their capacity to provide structural strength to the body.

Ratna : The minerals possessing gem quality are grouped as Ratna

Visha : Inherently highly poisonous plants are grouped as Visha.

Metals and Minerals

Rasa

Uparasa

Maharasa

Dhatu

Upadhatu

Ratna

Uparatna

Vishas and Upavishas

Animal origin substances

Sudha Varga- Shankha, shouktik, kapardik, praval etc

Samskaras in Rasashastra

Samskaras are the processing methods employed to transform the properties of the substances specifically to remove undesired properties and enhance desirable qualities.

Extremely important aspect in formulations since this allows the administration, metabolism, assimilation, assimilation of inorganic metals and minerals in the body.

Various samskaras involved in purification process of Mercury and other metals. metals believed to have natural impurities called as ‘ Doshas’ (Fault/defect/harmful element).

Remove doshas for oral administration

Methods (In general applicable to all)

1 Shodhana (Purification/cleansing) and

2 Marana- process by which metals and minerals are grinded with liquids and then dried and made into fine ash form by heat/ Incineration

Mercury is utilized in Medicine and Alchemy.

Method of putting Mercury to medicinal use is known as ‘Deha vaada’ (Deha- Body, Vaada- science/knowledge).

Use of mercury in Alchemy is termed as ‘Dhaatu vaada’ (Dhatu-metals and minerals).

In medicine mercury is used (a) as a general medicine in diseased states and (b) as a ‘Rasayana’ (Rejuvenator) drug.

Purification procedure of mercury depends on its intended use.

Simple procedures such as washing and grinding with plant juices like betel leaf juice, garlic paste and lime water are prescribed when mercury is to be used as a drug in diseased state.

However intensive and complex processing is required when mercury is to be used as a ‘Rasayana’ (Rejuvenator medicinal substance) or it is to be used for the purpose of ‘Alchemy’.

Eight and eighteen independent procedures have to be carried out respectively for ‘Rasayana’ and ‘Alchemy’.

These procedures are grouped as ‘Ashtasanskara’ comprising eight and ‘Ashtaadasha sanskara’ comprising eighteen independent procedures.

Ashta – 8

Ashtadasha- 18

Samskaras- process of transformation of properties

Applicable to all the heavy metals and minerals used in Ayurvedic medicines

Safety of Rasa-aushasdhi (Rasashastra medicines)

  1. 1.0 1.1 1.2 Savrikar SS, Ravishankar B. Introduction to 'Rasashaastra' the Iatrochemistry of Ayurveda. Afr J Tradit Complement Altern Med. ;8(5 Suppl):66–82. doi:10.4314/ajtcam.v8i5S.1
  2. Gandhi, Piyush. (2014). Marana-As a Bio-nanotechnology of Ayurveda. Research and Reviews: Journal of Ayurvedic Science, Yoga and Naturopathy. 1. 12-18.